"Formulation” combines a drug with biologically inert materials to create a product with the desired properties. Properties that can be controlled by formulation include apparent solubility and dissolution rate, chemical stability, protein aggregation, and crystal polymorphic form. Research in formulation addresses the rates and mechanisms of chemical degradation reactions, the nucleation and growth of pharmaceutical crystals, and the development of novel excipients that stabilize the drug. The Department of Industrial and Molecular Pharmaceutics is a world leader in developing fundamental understanding and new technologies for formulating pharmaceutical solids.
- Stephen R. Byrn (Charles B. Jordan Professor) – Solid state formulation and stability of small molecules, pediatric formulation, reduced dose formulation
- Tonglei Li (Allen Chao Chair) – Intermolecular interaction and crystal packing, nucleation and phase transition, computation and visualization
- Eric J Munson (Professor and Department Head, Dane O. Kildsig Chair in Industrial and Molecular Pharmaceutics) – Solid state characterization of excipients, amorphous solid dispersions, protein formulation and stability
- Lynne S. Taylor (Retter Distinguished Professor of Pharmacy) – Amorphous solids, role of moisture in pharmaceutical solids, development of analytical methods to characterize solids
- Elizabeth M. Topp (Professor and director of the William D. and Sherry L. Young Advanced Manufacturing of Pharmaceuticals Institute ) – solid-state formulation and stability of biologics, control of protein aggregation